Mesotherapy and Lipolysis

Mesotherapy is a reference in the treatment of cellulite, while lipolysis is fundamentally useful for reducing ‘localized fat’ when there is no indication for liposuction.

What is mesotherapy and lipolysis?

Mesotherapy is the intradermal introduction of medicines into the pathology site to be treated in order to increase their effectiveness and reduce their side effects.

Lipolysis consists of infiltrating lipolytic drugs directly into the fat layer below the skin to induce chemical separation of triglycerides within the adipocyte and thereby decrease their number and size.

In both techniques, which can be combined, needles are used to reach and only target tissue.


What results can be obtained?

Mesotherapy is a reference in the treatment of cellulite while lipolysis is fundamentally useful for reducing ‘localized fat’ when there is no indication for liposuction. They may be important aids in body shaping in food or other programs (e.g., gastric balloon) to treat overweight.

Both techniques can be performed on any part of the body: abdomen, flanks, arms, thighs or knees as well as the neck (chin) or the face itself. Different zones can be treated simultaneously within certain limits.

It is recommended to perform a cycle of treatments and adjust their frequency and intensity according to clinical evolution. The results appear in the first weeks and consolidate after a few months as the fat deposits are mobilized and the skin becomes more uniform.


How do we do mesotherapy and lipolysis?

At Up Clinic we only use approved and safe drugs that are specifically selected for each situation. We use very thin needles and a recent application technique so that the treatment is well tolerated.

Each session takes about 15 minutes and normal life can be resumed immediately. In general, mesotherapy is performed weekly, and lipolysis is done monthly.

Side effects are rare, as long as the selection and combination of the different products to infiltrate is adequate and the depth of application is correct.


Complementary Treatments

In the case of cellulite, we generally use an integrated protocol of mesotherapy combined with other techniques, such as Accent® radiofrequency and carboxitherapy when there is an associated component of sagging.

Lipolysis can be enhanced by nutritional measures and Accent® radiofrequency to prevent sagging that may rise after fat mobilization.


Dr. Vítor Figueiredo

Dra. Renata Morais

Clinical case

Clinical case of Mesotherapy and Lipolysis

During consultation the doctor will discuss the procedure details with the patient, in all its phases and using images of similar cases as well as leveraging patient expectations.


Conheça as nossas instalações

A Up Clinic nasceu com o intuito de oferecer uma experiência de excelência na área de estética e bem-estar. As instalações da clínica em Lisboa foram criadas com o objectivo de proporcionar o máximo conforto num ambiente elegante e exclusivo, sem descurar a proximidade que caracteriza a equipa multidisciplinar da clínica.



Mesotherapy and Lipolysis are 30-minutes medical procedures that don’t need anesthesia. Both procedures haven’t internment or period of downtime and the final results are obtained within 4 to 8 weeks. The following inhibitions should be considered: 24h inhibition of physical activity, flying and sun exposure.


30 min


Doesn’t have


Doesn’t have


Doesn’t have


4 to 8 weeks

Physical activity inhibition

24 hours

Flying inhibition

24 hours

Driving inhibition

Doesn’t have

Sexual activity inhibition

Doesn’t have

Sun exposure inhibition

24 hours