Hyaluronic acid

Hyaluronic acid is a biodegradable and biocompatible molecule, produced synthetically in laboratories. Hyaluronic acid acts by expanding the tissue where they are placed. They are adaptable to a wide range of situations, from complete facial harmonization to isolated wrinkles and isolated areas of the face such as the lips.

What Is Hyaluronic acid and what is it used for?

Hyaluronic acid is a biodegradable and biocompatible molecule, synthetically produced in laboratories. It acts by expanding the tissue where it is placed. It is adaptable to a wide range of situations, from complete facial harmonization to isolated wrinkles, including specific areas of the face such as the lips. Its structure consists of multiple interconnected single chains, forming a mesh. The more complex this mesh is, the more consistent the hyaluronic acid gel will be. In other words, not all hyaluronic acid gels are the same, and the appropriate choice and application are crucial for a natural result.

Where Is Hyaluronic acid applied?

One of the main concerns of patients who seek Aesthetic Medicine consultation is the appearance of nasolabial folds and marionette lines. In these cases, the treatment almost invariably involves the need for facial restructuring, meaning the application of hyaluronic acid in strategic support points to achieve a lifting effect on adjacent tissues.

There are three main support points: the cheek region (cheekbones), the jawline, and the chin (the 3Ms). These points correspond to the areas most affected by the aging process, through bone resorption and the loss of fat compartments. By replenishing the lost volume in these regions, we create a force of tension and tissue elevation, reducing wrinkles and sagging resulting from the aging process.

The enhancement of these three prominences can also be done in younger individuals who wish to emphasize their facial contours, enhancing their beauty. The goal is to create lines of light and shadow, promoting a more chiseled face with a well-defined blush line and jaw contour. This look is also referred to as the “Top Model Look,” and it is what we aim to achieve with makeup.

This initial facial restructuring with hyaluronic acid can be complemented by other detail (or beautification) fillers, such as under-eye filler, temple filler, lip filler, or rhinomodeling.

How Much Hyaluronic acid Should Be Applied?

The amount of hyaluronic acid needed to achieve a satisfactory result varies and is personalized for each case. On average, a complete facial harmonization requires between 6 to 12 syringes (ml) of hyaluronic acid. However, since it is an exclusive and individualized treatment tailored to each person’s needs, it requires a prior medical evaluation.

What Are the Benefits of Hyaluronic acid?

  • Improvement of sagging skin
  • Reduction of signs of aging
  • Diminished wrinkles and creases
  • Enhancement of facial structure and contour
  • Improved hydration and skin quality

Who Is a Suitable Candidate for Hyaluronic acid application?

This treatment is suitable for anyone looking to address signs of aging, sagging skin, or wishing to improve the structure, contour, and proportions of their face for a more harmonious and beautiful appearance.

Complementary Treatments to Hyaluronic acid:

Hyaluronic acid application can be complemented with:

  • Botulinum toxin
  • Injectable collagen stimulators
  • Threads
  • Liftera (Micro- and macro-focused ultrasound)
  • Ablative or non-ablative laser treatments
  • Chemical peels
  • Microneedling with drug delivery
  • Profhilo
  • Skin boosters
  • Personalized skincare routine
  • Others

Contraindications for hyaluronic acid:

  • Allergy
  • Active and uncontrolled autoimmune disease
  • Active and uncontrolled inflammatory disease
  • Active local infection
  • Severe coagulation disorders
  • Individuals under 18 years old (relatively and dependent on indication and legal guardian authorization)
  • Pregnancy
  • Breastfeeding
  • Severe and uncontrolled psychological disorders


Dr. Vítor Figueiredo

Dr. Rui Lima

Dra. Renata Morais


Conheça as nossas instalações

A Up Clinic nasceu com o intuito de oferecer uma experiência de excelência na área de estética e bem-estar. As instalações da clínica em Lisboa foram criadas com o objectivo de proporcionar o máximo conforto num ambiente elegante e exclusivo, sem descurar a proximidade que caracteriza a equipa multidisciplinar da clínica.


A aplicação de preenchimentos é um procedimento médico e tem uma duração de 30 minutos. Não necessita de anestesia, pois é um procedimento indolor. É um procedimento que não tem internamento nem período de baixa e os resultados são imediatos. Deverão ser considerados as seguintes inibições para a aplicação de preenchimentos: 24h de inibição de atividade física, voar e de exposição solar.
Necessária consulta médica para diagnóstico e avaliação da existência de finalidade terapêutica.


30 min


Não tem


Não tem

de baixa

Não tem



Inibição de atividade física

24 horas

Inibição de

24 horas

Inibição de conduzir


Inibição de atividade sexual


Inibição de exposição solar

24 horas